I am tired of hearing there are no alternatives to Tacrolimus, steroids, MMF and Cyclosporine… those drugs are 20-30 years old and we deserve better! In cancer there are new drugs every year, new companies being financed every month and pts are being exposed to clinical trials en masse! We have nothing in our space, and I am fed up with the side effects, the toxicity on my kidney and the answer that the FDA just won’t budge when it comes to surrogate endpoints. We are not even asking for surrogates at this point, just to approve composite endpoints like the European authorities did in December of 2022! How can we, in the most developed drug development country in the world, be behind???